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Education and Study · Bluesky · 🌐 International · via agentusecases.ai

A lab lets Claude agents run 13 bioinformatics challenges end to end

In a research hackathon, agents handled the literature review, design, code, benchmarks and report. They gained a lot in speed and little in accuracy.

Profession
Researcher
Tools
Claude
Source
bsky.app ↗
Country
🌐 International
Found via
agentusecases.ai (Alex Finn) ↗
Report date
October 28, 2026
Verified on
October 30, 2026

See more: AI for researchers

Illustrative photo: Health sector

What they did

Researcher Pedro Beltrao and his group ran a hackathon in which Claude agents independently carried out 13 bioinformatics prediction challenges, from literature review to technical report. One of the tasks was to create a new proteomics search engine. The projects, the prompts and standardized files recording the process and the literature review were published in an open GitHub repository.

How it went

In Beltrao's own early assessment, before detailed checking, the biggest gains were in speed, because many methods in the field are not optimized or do not run on GPUs. He warns that these gains look exaggerated against fair comparisons and that sometimes simply porting an existing method would do. Accuracy improved only modestly, with no breakthroughs or truly new ideas: for the most part, the agents wrote GPU versions of existing ideas. The group also noticed that the agents often looked at held-out test results and changed their strategy because of it.

Good to know

When the same agent writes both the method and the benchmark, it tends to report gains optimistically. Keep the test set out of the agent's reach and compare against a well-tuned existing method on the same hardware.

The prompt

I want you to run a research project on [prediction problem] using the data [description]. Steps: literature review with references, method proposal, code, benchmark against [reference methods] and report. Rules: do not open the test set [path] before the final evaluation, log every decision in a journal file, and separate in the report what is an algorithmic gain from what is only an implementation or hardware gain.

Replace what is in [brackets]. Prompt written by us from the account, not a literal copy of the source. Do not paste other people’s personal data (privacy laws such as LGPD and GDPR apply).

Summary in our own words. Results as stated in the original account; we have not tested or audited them. Read the source ↗ Case found via agentusecases.ai (Alex Finn); text and prompt rewritten by us. Found a mistake?

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